Plant Transcription Factor Database
Previous version: v3.0
Lotus japonicus
AP2 Family
Species TF ID Description
Lj0g3v0037529.2AP2 family protein
Lj0g3v0075529.1AP2 family protein
Lj0g3v0092269.2AP2 family protein
Lj0g3v0151469.1AP2 family protein
Lj0g3v0254389.1AP2 family protein
Lj1g3v4578960.1AP2 family protein
Lj1g3v4578960.2AP2 family protein
Lj2g3v1891000.1AP2 family protein
Lj3g3v1778650.1AP2 family protein
Lj3g3v3107620.2AP2 family protein
Lj4g3v0708640.1AP2 family protein
Lj1g3v4241090.1AP2 family protein
Lj2g3v1034640.1AP2 family protein
Lj0g3v0037529.1AP2 family protein
Lj3g3v3107620.3AP2 family protein
Lj4g3v2120330.2AP2 family protein
Lj3g3v3245260.1AP2 family protein
Lj1g3v2952280.1AP2 family protein
Lj0g3v0151469.2AP2 family protein
Lj0g3v0092269.3AP2 family protein
Lj0g3v0092269.1AP2 family protein
Lj3g3v3107620.1AP2 family protein
AP2 Family Introduction

The AP2/ERF superfamily is defined by the AP2/ERF domain, which consists of about 60 to 70 amino acids and is involved in DNA binding. These three families have been defined as follows. The AP2 family proteins contain two repeated AP2/ERF domains, the ERF family proteins contain a single AP2/ERF domain, and the RAV family proteins contain a B3 domain, which is a DNA-binding domain conserved in other plant-specific transcription factors, in addition to the single AP2/ERF domain.

It has been demonstrated that the AP2/ERF proteins have important functions in the transcriptional regulation of a variety of biological processes related to growth and development, as well as various responses to environmental stimuli.

Genes in the AP2 family have been shown to participate in the regulation of developmental processes, e.g. flower development, spikelet meristem determinacy, leaf epidermal cell identity, and embryo development.

Toshitsugu Nakano, Kaoru Suzuki, Tatsuhito Fujimura, and Hideaki Shinshi.
Genome-wide analysis of the ERF gene family in Arabidopsis and rice.
Plant Physiol, 2006. 140(2): p. 411-32.
PMID: 16407444

Using an in vitro selection procedure, the DNA binding specificity of the two AP2 repeat containing protein ANT was found to be 5'-gCAC(A/G)N(A/T)TcCC(a/g)ANG(c/t)-3'. This consensus site is much longer than sites recognized by proteins containing a single AP2 repeat and neither AP2 repeat of ANT was alone capable of binding to the selected sequences, suggesting that both AP2 repeats make DNA contacts.

Nole-Wilson S, Krizek BA.
DNA binding properties of the Arabidopsis floral development protein AINTEGUMENTA.
Nucleic Acids Res. 2000 Nov 1;28(21):4076-82. Erratum in: Nucleic Acids Res 2001 Mar 1;29(5):1261.
PMID: 11058102